Life Sciences

Identifying Genetic Biomarkers

GeneGini enables Academic and Pharmaceutical Researchers to prognose, diagnose and sub-categorise more diseases with better accuracy and sensitivity.

Health and BiotechLife SciencesPharma

Novel Anti-TB Therapeutics

This project focuses on the development of drugs that target novel, unexplored biological pathways to treat Tuberculosis and tackle the global threat of drug resistant TB.

ComputingSoftware

Crystal clear - CrystalGrower

CrystalGrower is a tool to develop a greater understanding of how crystals grow at the nanoscale through simulation of crystal habit and surface topography that, in turn, helps predict and control functionality.

#crystalformation
#simulationsoftware
#nanoscale
#surfacetopography
The VEGA remotely operated vehicle (ROV) developed by The University of Manchester to access hard-to-reach spaces.

ComputingElectronicsHardware

University robotics technologies

The University of Manchester are developing innovative robotic solutions to carry out inspections and maintenance underground, underwater, and in confined spaces.

#robotics
#confinedspaces
#underground
#underwater

ComputingEngineering and ManufacturingSoftware

Silence is golden - compact attenuators for use in tight spaces

The University of Manchester have developed a novel approach to noise control, able to decimate decibels and provide unparalleled silence.

#attenuation
#noisecancellation
#resonator
image of plasters

Advanced MaterialsEngineering and Manufacturing

Self-healing plastics

The University of Manchester have developed a new class of bio-based self-healing epoxy systems.

#selfhealing
#plastics
#epoxy

Life SciencesMedtech

In the genes - Gene-cell therapies

Duchenne Muscular Dystrophy can devastate a person’s life, resulting in mobility limitation and heart failure. Now, the latest in gene technology is being used to offer targeted therapies to patients in order to bring expertise to this vital area.

#musculardystrophy
#genetics
#disease
X-rays of brains

Life SciencesMedtechPharma

Biotech brilliance - StrataStem Ltd

StrataStem Ltd is a spin-out biotechnology company seeking to transform the diagnosis and treatment of Alzheimer’s disease.

#stratastem
#alzheimers
#biotechnology

Chemistry and PhysicsEngineering and Manufacturing

Novel transfer chute

The academic team at The University of Manchester have developed a new design of transfer chute, with a low cost-to-benefit ratio, to solve a problem so intrinsic with chutes designed before it.

#transferchute
#granularmaterials
#manufacturing

Life SciencesMedtech

Rheumatoid relief

While therapies to help with Rheumatoid arthritis have become more successful in recent years, there still remains a significant amount of patients for whom the treatment has no effect. A new, more effective method for targeting patients that will respond to treatment could result in better outcomes and cost savings.

#arthritis
#treatment
#immunoprofiling
Patient waiting in hospital, looking towards a light in the corridor

MedtechSoftware

Adept ADAPTations - ADAPT

Even when a person has managed to beat cancer, it is an unfortunate fact that complications can arise years in the future due to the treatments they received for their cancer. There is therefore an urgent need to address this issue with measures to track and trace cancer treatment complications down the line.

#ADAPT
#cancer
#treatment
virus

Chemistry and PhysicsHealth and BiotechPhysical Sciences

Antiviral agents

With the devastating effects of the Covid-19 pandemic still being felt around the globe, there is an ever-greater need for antiviral protection. Broad-spectrum antiviral agents have the potential to destroy a wide range of viruses and can be used in a wide variety of applications beyond drug modalities. This new platform technology is suitable for incorporation into antiviral coatings and could therefore transform the practice of sterilisation forever.

#antiviral
#covid-19
#sterilisation

ComputingHardware

Breath of fresh air - Riptron Ltd

Riptron is developing a low cost, chip-based gas sensor to monitor harmful gases in our cities and homes. With an increasing awareness of pollution and air quality, there has never been a greater drive to ensure the air we breathe is as clean as possible.

#riptron
#pollutionsensor
#cleanair

Health and BiotechLife SciencesMedtech

Dysphagia treatment - Phagenesis

Invaluable treatment to transform the lives of patients who have difficulty swallowing.

#phagenesis
#dysphagia
#treatment

ComputingSoftware

Whirlwind development - TornadoVM

TornadoVM: A practical and efficient framework for accelerating managed programming languages on heterogeneous hardware accelerators

#tornadovm
programming
#software

Life SciencesPharma

Spotting cell senescence - SenTraGor

SenTraGor is an innovative, easy-to-use reagent for the reliable detection of Senescence in cells.

#sentragor
#senescence
#disease
#testing
#aging

Health and BiotechLife SciencesPharma

Vaccination innovation – Novel virus-like particle platform

A novel virus-like particle platform which could transform vaccine antigen delivery and gene therapy.

#vaccine
#virus-likeparticles
#genetherapy

Life SciencesPharma

Stop bugging me! - Antimicrobial peptides

Addressing concerns regarding super-resistant diseases which even the strongest medicines cannot touch, this peptide-packed technology is a remedy for the post-antibiotic age.

#antimicrobial
#peptides
#antibiotic
#pharma
abstract image of tendon

Health and Biotech

Fixing Achilles

An innovative device designed to be delivered by keyhole surgery which specifically addresses the biology of a regenerating tendon to improve outcomes for patients.

#tendon
#tendonrepair
#biotech

Advanced MaterialsEngineering and Manufacturing

Still waters - Watercycle Technologies Ltd

Watercycle Technologies have developed a high flux, low fouling membrane which, when coupled with its advanced membrane distillation (MD) technology, can treat highly concentrated wastewater from industries as diverse as desalination, mining, oil & gas, textiles, food & beverage, and others. The system has the additional advantage of having low running costs as the process is driven by thermal solar power or low grade waste heat from an industrial process.

#Watercycletechnologies
#water
#engineering
#waterfilter
#dirtywater

Health and BiotechSoftware

On-the-move support for schizophrenia - ACTISSIST

ACTISSIST is a new app developed at The University of Manchester to provide therapy on-the-move for those with severe mental illnesses such as schizophrenia.

#actissist
#schizophrenia
#therapy

Life SciencesMedtech

Targeted tumour treatment

Current clinical solutions are not as effective as they could be, with certain cancers and tumours evading treatment. This unmet need is being met with a Hypoxia-beating new drug.

#tumours
#therapy
#hypoxia

Life SciencesMedtech

Stem cell super-test

Testing stem cell health without testing stem cells! The great hope for future medical miracles has been made even easier with this breakthrough.

#stemcells
#testing
#pluripotent

Advanced MaterialsEngineering and Manufacturing

Dreamweaving - 3D weaving technique

3D weaving technique able to weave fibre yarns into any number of required preforms, this cutting-edge machine can be easily adopted by current manufacturers to produce incomparable fabrics.

#weaving
#materials
#fabric

Advanced MaterialsEnergy and EnvironmentEngineering and Manufacturing

Biodegradable plastic

This innovative technology offers a green solution to the plastic industry through the development of never-been-done-before materials.

#biodegradable
#plastic
#enviroment

ComputingEnergy and EnvironmentSoftware

Going underground - VRGeoscience Ltd

Spinout business VRGeoscience Ltd develop 3D technology to better understand deep underground structures.

#software
#geology
#undergroundmapping

Life SciencesMedtech

Sight for spore eyes - Fungal keratitis treatment

Damage to the eye as a result of fungal infection remains a pressing issue, with early intervention not always being possible and long-term vision loss being common. This new technology can be the quick and accurate intervention needed to prevent permanent impairment.

#fungalkeratitis
#visionloss
#diagnosis

Engineering and ManufacturingHardware

Multi-material printing for additive manufacturing

Combining cutting-edge hardware with laser-focused software, The University of Manchester have developed a 3D printing solution a cut above the rest.

#3Dprinting
#additivemanufacturing
#laser

Life SciencesMedtechSoftware

Breathe easy - Clin-e-cal Ltd

Clin-e-cal is a spinout digital health company from The University of Manchester aiming to transform respiratory care.

#clin-e-cal
#respiratory
#asthma
A 3D Rendering of a nerve structure on a white background.

Life SciencesMedtech

Touching a nerve - Polynerve

Surgery to take nerves from one area of the body to replace those lost in another are a common solution for nerve injuries. However, these surgeries incur their own difficulties, such as loss of sensation and pain. Polynerve is a new device which will revolutionise the field of nerve repair.

#polynerve
#nerveinjury
#medtech

ComputingSoftware

Hyper-realistic display images - Revised colour mapping

With an upgrade on the industry-standard trichromatic colour space, The University of Manchester have revised colour mapping to improve image quality and transform the palate of visual image creation.

#colourmapping
#photoreceptors
#imaging

Life SciencesMedtechPharma

Microbiology miracle – MicroBioSensor Ltd

MicroBioSensor is a medical device company manufacturing point of care diagnostics for bacterial infections.

#microbiosensor
#diagnostic
#microbiology

Energy and EnvironmentEngineering and Manufacturing

A virtuous circle - NovaCrack

NovaCrack is a rapid depolymerisation process that transforms mixed plastic waste into high-value hydrocarbons which can be converted back to virgin polymers, thereby closing the loop for a truly circular economy.

#novacrack
#depolymerisation
#plastics
#recycling

Life SciencesMedtechSoftware

Dental development - Manchester Imaging Ltd

Manchester Imaging Ltd is a successful spinout from The University of Manchester using software solutions to capture cavities and train the next generation of dentists.

#manchesterimaging
#dentistry
#toothdecay

Life SciencesMedtech

Rapid diagnosis for Parkinson’s - SebOMIX Ltd

A non-invasive test for Parkinson’s Disease potentially offering rapid, non-invasive diagnosis before the onset of symptoms.

#sebomix
#parkinsons
#testing

Life SciencesMedtech

Super MAN stem cells - Ethical stem cells

The procurement of stem cells, which are used in ever-more effective treatments for conditions such as Alzheimer’s disease, is a source of moral concern for many opposed to the practice. However, a new ethical solution may mitigate this flashpoint moral quandary.

#stemcells
#embryos
#cells

Life SciencesMedtech

Targeted cancer therapy - ManTRa DX

ManTRa DX have developed tumour-site-specific gene expression signatures to assess hypoxia which has the potential to deliver major advances in personalised cancer medicine.

#mantradx
#tumours
#cancer
#treatment

Health and Biotech

Light sight

A light receptor with frequency-dependent activation level.

#eyehealth
#lightreceptiveproteins

Life SciencesMedtech

The cellular level – eNAMPT stimulation

A build-up of Nicotinamide Adenine Dinucleotide (NAD) in the body can result in the onset of various diseases and poor health outcomes. The University of Manchester have developed a new series of small molecule compounds, specifically designed to stimulate eNAMPT dimerization and have demonstrated these have potent activity leading to a corrective effect in in vitro and in vivo phenotypic models of diabetes. These could also have benefits in the treatment of a number of other diseases.

#enampt
#nicotinamide
#dimerization

ComputingElectronicsSoftware

Pixel perfect - SCAMP vision sensor

SCAMP is a low-power, high-speed machine vision device using cutting image sensors to execute a variety of vision algorithms.

#scamp
#machinevision
#pixels
Collection of MRA brain or Magnetic resonance angiography image ( MRA ) of cerebral artery in the brain for detect stroke disease.

Life SciencesMedtech

Protease positivity

Currently, the only licensed therapy for ischaemic stroke remains largely unsuitable for many due to patients being naturally resistant to the treatment. As a result, there remains an urgent need for an accurate alternative for this vital treatment.

#protease
#therapy
#stroke
#ischaemic

Software

The future of farming - FOTENIX Ltd

FOTENIX Ltd have developed a cutting-edge imaging system and analytical software to help growers and farmers improve crop yields, spot early signs of ripening and identify indications of disease or dehydration quick enough to take remedial action. This solution offers results far more reliable than the human eye and can be fully mobile enabling real time imaging and analysis to be carried out literally ‘in the field’.

#fotenix
#farming
#imaging
#software

A.I.ComputingHardware

Robotics for everyone - Puzzlebot

Manchester Robotics have a mission to globalise access to learning and development tools for robotics. In doing so, they intend to close the £96bn/year STEM skills gap in the manufacturing workforce and democratise educational resources for society’s most disruptive technologies: robotics, automation and AI.

#puzzlebot
#robotics
#learning
#globalisation

Life SciencesPharma

The missing link - Link Biologics

Link Biologics is developing Link_TSG6, a protein biological, to treat common inflammatory and degenerative disorders of the ocular and musculoskeletal systems.

#linkbiologics
#eyedisease
#osteoarthiritis
Soldering robotics hardware

ComputingHardware

MONA robotic platform - Ice Nine Ltd

Ice Nine Ltd is a spin-out business which specialises in innovative robotic solutions, in industries ranging from nuclear decommissioning to research and education.

#icenine
#robotics
#programming

Advanced MaterialsEngineering and Manufacturing

Improving elastomers - Grafine Ltd

Grafine Ltd is the ground-breaking development and consultancy business that has a successful track record of maximising the performance of elastomers using a range of 2D materials, including grafine.

#grafine
#nanomateirals
#elastomers

Advanced MaterialsEngineering and Manufacturing

Invisibility cloak - SmartIR Ltd

SmartIR’s innovative tiles have ability to control visible colour and infrared light creating limitless applications. Dynamic infrared patterns, thermal management solutions, and adaptive camouflage systems are just some the developments enabled by the manipulation of infrared light.

#smartir
#thermal
#light
#infrared

A.I.ElectronicsHardwareSoftware

Flexible thinking - Atomic Mechanics Ltd

A completely new type of human machine interface (HMI) which is flexible, transparent and robust.

#HMI
#humanmachineinterface
#graphene
#eskins

ComputingSoftware

Faster insight for data scientists - The Data Value Factory

The Data Value Factory is a spin-out that have created software to automate many of the previously manual aspects of preparing data for analysis, reducing time to insight.

#software
#data
#analysis
#preparingdata
Caspars Castle digital game

Life SciencesSoftware

Vision quest - Caspar's Castle

Testing the visual field of children is difficult, resulting in inaccurate and unreliable outcomes which can lead to sight loss and other conditions. The University of Manchester has hopes to change that with novel software which is quite the spectacle.

#childsightloss
#casparscastle
#visionsoftware
#optometry

ComputingMedtechSoftware

Digital doctors - VREvo Ltd

With cutting-edge technology as sharp as a scalpel, VREvo Ltd has the means to train a new generation of healthcare professionals with virtual reality, using simulated surgeons, pretend patients, and all manner of virtual organs to get results.

#virtualreality
#vrevo
#operatingtheatre
#simulation

A.I.ComputingEnergy and EnvironmentEngineering and ManufacturingHardware

Second wind

An AI-empowered system enabling wind farm operators to lower the excessive cost of maintaining their operational assets.

#windturbine
#AI
#windfarm
#offshore
#onshore
illustration of eye

Health and Biotech

A vision of success - Complement Therapeutics Ltd

Taking on two devastating immune system diseases, AMD and GA, Complement Therapeutics Ltd is developing new strategies to enhance one of the most promising areas in patient care.

#complementtherapeutics
#immunesystem
#therapy

Life SciencesPharma

Homeostatic hope

A new compound targeting the protein Pumilio as an antiepileptic drug.

#protein
#pumilio
#antiepileptic
#pharma

Chemistry and Physics

Boiling stones - Zeolites

Zeolites, derived from the Greek words zeo (to boil) and lithos (stone), are aluminosilicate minerals that seemed to froth or boil when heated in a blowpipe in flame. Zeolites are used in a lot of industries due internal pore structure. We have developed a novel method of making zeolites with a tailored porosity in a timely and energy efficient way that also improves its performance in catalysis.

#zeolites
#catalysis
#mesopores
Cutting-edge resistors which are thinner, deeper, faster.

Advanced MaterialsEngineering and ManufacturingHardware

Novel nanofabrication - Sci-Tron Ltd

Sci-Tron technology, with unique and unparalleled etch sensitivity, is unlocking industry potential to develop groundbreaking products and boundary-pushing new applications.

#sci-tron
#resist
#nanofabrication